What is this medication for?
Mitomycin belongs to the group of cancer-fighting medications known as antineoplastics, and specifically to the group of antineoplastics called actinomycins. Mitomycin causes the death of cancer cells by interfering with their growth and reproduction. It is used alone or in combination with other antineoplastic medications, radiation, or surgery to treat certain types of cancer of the stomach and pancreas.
Your doctor may have suggested this medication for conditions other than those listed here. If you have not discussed this with your doctor or are not sure why you are taking this medication, speak to your doctor.
What form(s) does this medication come in?
Mutamycin® is available as:
- injectable
- 5 mg per vial
- 20 mg per vial
- 40 mg per vial
Some medications may have other generic brands available. Always ask your doctor or pharmacist about the safety of switching between brands of the same medication.
How should I use this medication?
The recommended dose and dosing schedule of mitomycin varies according to the specific disease being treated, the response to therapy, and the other medications or treatments being used. The dose administered is also based on body size. Mitomycin is usually injected into a vein. Very careful handling of this medication is required. It is always given under the supervision of a doctor in a hospital or similar setting with access to sterile equipment for preparation.
As well as interfering with the genetic material DNA of cancer cells, mitomycin can interfere with some of your normal cells. This can cause a number of side effects such as mouth sores. Mitomycin may cause nausea and vomiting, but it is important to keep using this medication even if you feel ill. Your doctor, nurse, or pharmacist can advise you on how to reduce the effects of nausea and vomiting. Keep track of any side effects and report them to your doctor as suggested in the section, "What side effects are possible with this medication?"
Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.
Store this medication at room temperature, protect it from light and moisture, and keep it out of the reach of children.
Who should NOT take this medication?
Mitomycin should not be used by anyone who:
- is allergic to mitomycin or any ingredients of the medication
- has blood clotting disorders or any increased bleeding tendencies
- has low blood platelet counts